Treating Psychotic Symptoms in Persons With Dementia

By Crisis Prevention Institute | 0 comments
Treating Psychotic Symptoms in Persons With Dementia

In May 2011, the Office of the Inspector General published a report titled Medicare Atypical Antipsychotic Drug Claims for Elderly Nursing Home Residents.

The report was based on information that was collected from January through June 2007. It stated that:

  • 14 percent of elderly nursing home residents had Medicare claims for atypical antipsychotic drugs; and
  • 83 percent of Medicare claims for atypical antipsychotic drugs for elderly nursing home residents were associated with off-label conditions;
  • 88 percent were associated with the condition specified in the FDA boxed warning.

(In the United States, the Food and Drug Administration (FDA) approves medications for specific uses. If a medication is used for any other use (other than the approved uses), this is considered an "off-label" use. A box warning means that medical studies indicate that the drug carries a significant risk of serious or even life-threatening adverse effects.)


There is certainly much debate about the use of these medications for persons with dementia. These medications are prescribed to treat agitation and symptoms of psychosis in persons with dementia who are living in all settings, including long-term care facilities, assisted-living facilities, and at home with a caregiver. Agitation can be dangerous and upsetting for the person with dementia and the caregiver/family. However, the use of antipsychotic drugs in persons with dementia can have serious adverse effects, and may only mask the problem instead of alleviating it.   


The Behavior Is Likely a Form of Communication

Agitation is a common problem seen in persons with dementia, as are actions that appear delusional. The first step to lessen the problem is to discover and treat the cause for the psychotic symptoms. There is often a simple explanation for these changes. 

Persons with dementia lose the ability to communicate verbally as the disease progresses. However, the individual continues to communicate by relying on other forms of communication, such as facial expressions, gestures, body language, and negative behaviors. These behaviors are often the expression of fear, frustration, pain, or just an inability to express an unmet need. For example, the person may not be able to verbally communicate discomfort related to constipation, headache, or a mild infection.

The following are some common communications that are expressed through behaviors:

  • Persons with dementia misinterpret their environment. They may hear someone talking on the TV and not realize that the voice is coming from the TV, so they may respond to the person on TV. If the voice is angry, the person may respond angrily. This may appear delusional, but the cause is a misinterpretation of the environment.

  • If the environment is noisy, chaotic, or overstimulating, the person may express fear by becoming agitated and anxious.

  • Persons with dementia need reassurance because they do not always recognize their environment. The person often reverts to memories of a childhood home, where the person felt safe, comfortable, and loved, and the person may start to physically seek that environment. During these moments, the person with dementia may not recognize the current environment as a place in which he has been living, and he may become agitated and attempt to leave. This disorientation is a result of his ability to use his strong long-term memory to remember and seek a place (and feeling) of safety.

  • Persons with dementia often appear egocentric, to the point that they may become upset or irritable if someone else is in their room or sitting in their chair. This egocentricity is the person’s best ability. The person has lost the ability to consider other people's needs, and is focused on self-protection.

  • Persons with dementia continue to have the basic need for a sense of productivity and purpose. They may have lost the ability to sequence themselves through a familiar task, but they still have the need to be engaged in valued activities. If boredom sets in, the person with dementia may express this through irritability and/or agitation.

  • Persons with dementia continue to have a need for relationships, even when their best ability is to respond to meaningful stimulation. They continue to have the basic need for love and interaction. Isolation and/or lack of stimulation can easily lead to agitation and depression.

These are just some of the reasons that a person with dementia may present with agitation. There is a cause, a trigger, that needs to be remedied or satisfied.


Once the person becomes agitated, it is often difficult to defuse the situation. Defusing the situation takes time, the right environment, and the right approach from the caregiver. However, if there is a concerted effort to discover the trigger for the agitation, then this agitation may be prevented in the future. It is about discovering the trigger and being proactive, not reactive.



In order to prevent/minimize negative behaviors, we need to understand the communication of the person with dementia, and listen. Often, considerable observation is required to understand the meaning of the behaviors. Possible medical problems need to be considered. And it is helpful to look for and record any patterns of behavior. For example, when the person presents with agitation, consider who is present, where and when the agitation occurs, and what your thoughts are about why the agitation is occurring. This will lead to a systematic way of determining the probable cause.

A nonpharmacological approach should be the first step in treating the psychotic symptom. If we can discover the trigger, then we can address the problem or need and prevent further agitation. With a proactive approach, it is likely that the use of antipsychotic medications will be reduced.


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